Airway responsiveness in CD 38 - deficient mice in allergic airway disease : studies 1 with bone marrow chimeras 2 Alonso
نویسندگان
چکیده
Department of Surgical & Radiological Sciences, University of California, Davis, CA; 5 Department of Veterinary and Biomedical Sciences, University of Minnesota, St. Paul, 6 MN; Department of Medicine, University of Pennsylvania, Philadelphia, PA; 7 Departments of Immunology and Medicine, Mayo Clinic, Rochester, MN; and Trudeau 8 Institute, Saranac Lake NY, and currently Department of Microbiology, University of 9 Alabama at Birmingham, Birmingham, AL. 10
منابع مشابه
Airway responsiveness in CD38-deficient mice in allergic airway disease: studies with bone marrow chimeras.
CD38 is a cell-surface protein involved in calcium signaling and contractility of airway smooth muscle. It has a role in normal airway responsiveness and in airway hyperresponsiveness (AHR) developed following airway exposure to IL-13 and TNF-α but appears not to be critical to airway inflammation in response to the cytokines. CD38 is also involved in T cell-mediated immune response to protein ...
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